hrp0095p1-552 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Final adult height in children with central precocious puberty – a retrospective study

Knific Taja , Lazarevič Melisa , Žibert Janez , Obolnar Nika , Aleksovska Nataša , Šuput Omladič Jasna , Battelino Tadej , Avbelj Stefanija Magdalena

Background: Central precocious puberty (CPP) is a premature activation of the hypothalamic-pituitary-gonadal axis. One of its negative effects is lower final adult height (FAH) due to premature epiphyseal closure. GnRH analogues act by desensitizing GnRH receptors and stopping the progression of puberty and prolonging growth period.Objectives: We aimed to evaluate the effect of the GnRH analogue on FAH and identify facto...